Kate has always been a wanderer. A well-published author, married many times, she has lived a life rich with exploration of the natural worlds and the human soul. Now, at fifty-seven, she leaves her lover, Yolo, to embark on a new excursion, one that beginds on the Colorado River, proceeds through the past, and flows inexorably into the future. As Yolo begins his own parallel voyage, Kate encounters celibates and lovers, shamans and snakes, memories of family disaster and marital discord, and emerges at a place where nothing remains but love.